1.
Egyptian Journal of Pharmaceutical Sciences. 1996; 37 (1-6): 291-302
in English
| IMEMR
| ID: emr-40799
ABSTRACT
Uridine and 4-thiouridine were converted into the corresponding 2,3-o-isopropylidene-5-thiocyanato derivatives. Then, each resulted derivative was reacted individually with both of ethyl alpha- chloroacetoacetate, ethyl alpha-bromobenzoylacetate and ethyl bromo pyruvate. Furthermore, these 5-thiocyanato products were transformed into the corresponding 5-mercapto analogues. The produced analogues were undergo ring formation to give the corresponding 4,5-cyclized pyrimidine derivatives
Subject(s)
Thiouridine/chemistry , Esters/chemistry , Uridine/analogs & derivatives , Thiouridine/analogs & derivatives
2.
Egyptian Journal of Pharmaceutical Sciences. 1996; 37 (1-6): 423-9
in English
| IMEMR
| ID: emr-40810
ABSTRACT
The present paper described work directed towards reactions of both of 2',3',5'-tri-O-acetyl uridine and its 2-thioanlogue with either of 2H- pyran-2-one, 4,6-dimethyl-2H-pyran-2-one and 2,3-bis [dibromomethyl] benzene to afford cycloaddition products